A review of twelve Southern Chinese children whose myasthenic symptoms started within
the first two years of life and followed up for one to sixteen years showed that,
unlike some previous reports on non-Chinese children, the majority had only ocular
myasthenia. Response to pyridostigmine was satisfactory and spontaneous remissions
were frequent. Although more boys than girls were affected, familial myasthenia occurred
in none. Serum acetylcholine receptor antibodies were not elevated in the majority.
An association with HLA A11 and BW 46 needs further confirmation.
Myasthenia gravis - Onset under two years - Ocular myasthenia in infants
